The Oxford classification as a predictor of prognosis in patients with IgA nephropathy

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The Oxford classification as a predictor of prognosis in patients with IgA nephropathy.

BACKGROUND In 2009, the Oxford classification was developed as a pathological classification system for immunoglobulin A nephropathy (IgAN) to predict the risk of disease progression. The aim of this retrospective study was to evaluate the clinical and pathologic relevance of the Oxford classification in Korean patients with a pathologic diagnosis of IgAN. PATIENTS AND METHODS We reviewed the...

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Validating the oxford classification of IgA nephropathy.

The evolution of patients with IgA nephropathy (IgAN) varies greatly, and predictive tools are needed to assess confidently the risk for progression. Although in many studies clinical risk factors such as hypertension and proteinuria have consistently been linked to outcome, the independent value of pathology remains debated. Pathologists have developed a number of classifications over the year...

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The Oxford classification of IgA nephropathy: single centre experience.

The Oxford classification for the pathological classification of a glomerular disease in IgA nephropathy was established and published in 2009. Four of the pathological variables: 1) mesangial hypercellularity score, 2) segmental glomerulosclerosis, 3) endocapillary hypercellularity and 4) tubular atrophy/interstital fibrosis were presented as having value in predicting renal outcome in this gl...

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The new Oxford Clinico-Pathological Classification of IgA nephropathy.

The new Oxford Classification of the Pathology of IgA nephropathy originated from an international collaborative effort of the Working Group of the International IgA Nephropathy Network and Renal Pathology Society. It provides a new common language to categorizing glomerular and tubulo-interstitial lesions in IgA nephropathy having a proved effect on progression. Although retrospective in desig...

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The Oxford Classification predictors of chronic kidney disease in pediatric patients with IgA nephropathy.

OBJECTIVE The Oxford Classification for Immunoglobulin A nephropathy (IgAN) identifies pathological variables that may predict the decline of renal function. This study aimed to evaluate the Oxford Classification variables as predictors of renal dysfunction in a cohort of Brazilian children and adolescents with IgAN. METHODS A total of 54 patients with IgAN biopsied from 1982 to 2010 were ass...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2011

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfr295